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There are 12 twelve-letter words containing A, C, E, M, T and X

ANTICLIMAXESanticlimaxes n. Plural of anticlimax.
anti-climaxes n. Plural of anti-climax.
ANTICLIMAX n. the usually sudden transition in discourse from a significant idea to a trivial or ludicrous idea.
AXISYMMETRICaxisymmetric adj. Exhibiting symmetry around an axis; exhibiting cylindrical symmetry.
axi-symmetric adj. Alternative form of axisymmetric.
AXISYMMETRIC adj. symmetrical in respect to an axis, also AXISYMMETRICAL.
CHEMOTAXISESCHEMOTAXIS n. orientation of an animalcule relative to a chemical substance.
COMPLEXATIONcomplexation n. (Chemistry) The formation of a complex.
COMPLEXATION n. a complex.
EXANTHEMATICexanthematic adj. Of or pertaining to exanthem.
EXANTHEMATIC adj. of or like an exanthem, a skin eruption, esp. accompanied by fever, also EXANTHEMATOUS.
EXCLAMATIONSexclamations n. Plural of exclamation.
EXCLAMATION n. a sharp or sudden utterance.
EXCLAMATIVESEXCLAMATIVE n. a word or sentence that denotes an exclamation.
EXOPHTHALMICexophthalmic adj. Of, or relating to exophthalmos.
exophthalmic adj. Having prominent eyeballs.
EXOPHTHALMIC adj. pertaining to or marked by protrusion of eyeball.
EXTRAMUSICALextramusical adj. Apart from and in addition to music.
EXTRAMUSICAL adj. lying outside the province of music.
HAEMATOXYLICHAEMATOXYLIC adj. of or like haematoxylin.
HEXAMETRICALhexametrical adj. Hexametric; consisting of six metrical feet.
HEXAMETRICAL adj. of verse, written in hexameters, also HEXAMETRAL, HEXAMETRIC.
XERODERMATICxerodermatic adj. Exhibiting or relating to xeroderma.
XERODERMATIC adj. relating to xeroderma, dryness of skin.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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