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There are 8 twelve-letter words containing 2A, C, M, T and X

ANTICLIMAXESanticlimaxes n. Plural of anticlimax.
anti-climaxes n. Plural of anti-climax.
ANTICLIMAX n. the usually sudden transition in discourse from a significant idea to a trivial or ludicrous idea.
EXANTHEMATICexanthematic adj. Of or pertaining to exanthem.
EXANTHEMATIC adj. of or like an exanthem, a skin eruption, esp. accompanied by fever, also EXANTHEMATOUS.
EXCLAMATIONSexclamations n. Plural of exclamation.
EXCLAMATION n. a sharp or sudden utterance.
EXCLAMATIVESEXCLAMATIVE n. a word or sentence that denotes an exclamation.
EXTRAMUSICALextramusical adj. Apart from and in addition to music.
EXTRAMUSICAL adj. lying outside the province of music.
HAEMATOXYLICHAEMATOXYLIC adj. of or like haematoxylin.
HEXAMETRICALhexametrical adj. Hexametric; consisting of six metrical feet.
HEXAMETRICAL adj. of verse, written in hexameters, also HEXAMETRAL, HEXAMETRIC.
TOXICOMANIAStoxicomanias n. Plural of toxicomania.
TOXICOMANIA n. a morbid craving for poisons.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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