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There are 20 ten-letter words containing 2A, C, E and 2M

ACADEMISMSacademisms n. Plural of academism.
ACADEMISM n. the doctrines of the Academic philosophy.
AMPHIMACERamphimacer n. A metrical foot consisting of an unaccented syllable between two accented syllables; a cretic.
AMPHIMACER n. a foot of three syllables, the middle one short and the others long, as in 'castitas'.
CLAWHAMMERclawhammer n. Alternative form of claw hammer.
claw␣hammer n. A hammer with two prongs protruding back from the head to allow for removing nails from wood.
claw␣hammer n. (Music, uncountable) A fingerpicking technique primarily used by banjo players, but also by some guitarists.
COCKAMAMIEcockamamie n. (US, chiefly dated) A decal, a design that can be transferred to a surface.
cockamamie n. A foolish or ridiculous person.
cockamamie adj. (Informal) Foolish, ill-considered, silly, unbelievable.
DECAGRAMMEdecagramme n. (British spelling) Alternative spelling of decagram.
DECAGRAMME n. a weight of the metric system; ten grams, also DECAGRAM, DEKAGRAM.
IMMACULATEimmaculate adj. Absolutely tidy, having no blemish or stain.
immaculate adj. (Zoology) (botany) Lacking blotches, spots, or other markings.
immaculate adj. (Figurative) containing no mistakes.
IMMANACLEDimmanacled v. Simple past tense and past participle of immanacle.
IMMANACLE v. (Milton) to put in manacles.
IMMANACLESimmanacles v. Third-person singular simple present indicative form of immanacle.
IMMANACLE v. (Milton) to put in manacles.
JACKHAMMERjackhammer n. A portable percussive power tool that combines a hammer and chisel used to drill or break hard matter…
jackhammer v. (Intransitive) To use a jackhammer.
jackhammer v. (Transitive) To break (something) using a jackhammer.
MACADAMISEmacadamise v. Alternative form of macadamize.
MACADAMISE v. to cover a road with small broken stones, also MACADAMIZE.
MACADAMIZEmacadamize v. To cover, as a road, or street, with small, broken stones, so as to form a smooth, hard, convex surface.
MACADAMIZE v. to cover a road with small broken stones, also MACADAMISE.
MACHINEMANmachineman n. (Historical) A man who manages the working of a machine, especially in a printing office.
MACHINEMAN n. a person who oversees the working of a machine.
MATCHMAKERmatchmaker n. Someone who finds suitable dates or marriage partners for other people.
matchmaker n. (By extension) Someone who arranges professional boxing matches.
matchmaker n. Someone who makes matchsticks.
MATCHMAKESmatchmakes v. Third-person singular simple present indicative form of matchmake.
MATCHMAKE v. to bring suitable people together for marriage.
MATHEMATICmathematic adj. (Archaic) mathematical.
MATHEMATIC adj. related to mathematics, also MATHEMATICAL.
MELOMANIACmelomaniac n. One with an abnormal fondness of music; a person who loves music.
MELOMANIAC n. an abnormally dedicated musical fan.
MYCETOMATAmycetomata n. Plural of mycetoma.
MYCETOMA n. a chronic fungus infection leading to nodules that discharge oily pus.
PARAMECIUMparamecium n. An oval-shaped protozoan organism of the genus Paramecium.
Paramecium prop.n. A taxonomic genus within the family Parameciidae – a ciliophore widely used as a model organism and for education.
PARAMECIUM n. a genus of tiny animals including the slipper animalcule, also PARAMAECIUM, PARAMOECIUM.
SARCOLEMMAsarcolemma n. (Anatomy) A thin cell membrane that surrounds a striated muscle fibre.
SARCOLEMMA n. the cell membrane enclosing a muscle fibre.
TACKHAMMERSorry, definition not available.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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