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There are 11 words containing A, F, 2S and X

EXSUFFLATESexsufflates v. Third-person singular simple present indicative form of exsufflate.
EXSUFFLATE v. to blow away; to exorcise.
EXSUFFLATIONSexsufflations n. Plural of exsufflation.
EXSUFFLATION n. expiration; exorcism by blowing.
FLAXSEEDSflaxseeds n. Plural of flaxseed.
flax␣seeds n. Plural of flax seed.
FLAXSEED n. the seed of flax.
FLEXITARIANISMSFLEXITARIANISM n. a semi-vegetarian diet involving the practice of eating mainly vegetarian food but making occasional exceptions for e.g. social reasons.
FOXSHARKSfox␣sharks n. Plural of fox shark.
FOXSHARK n. a large long-tailed shark, aka thresher.
SAXIFRAGACEOUSsaxifragaceous adj. (Botany) Of or relating to an order of plants (Saxifragaceae) of which saxifrage is the type.
SAXIFRAGACEOUS adj. belonging to the saxifrage family.
SAXIFRAGESsaxifrages n. Plural of saxifrage.
SAXIFRAGE n. a kind of rock plant.
SUFFIXATIONSsuffixations n. Plural of suffixation.
SUFFIXATION n. the act of creating a suffix.
SULFADOXINESSULFADOXINE n. a drug used to prevent and treat malaria, also SULPHADOXINE.
TRANSFIXEStransfixes n. Plural of transfix.
transfixes v. Third-person singular simple present indicative form of transfix.
TRANSFIX v. to impale.
TRANSFIXIONStransfixions n. Plural of transfixion.
TRANSFIXION n. the act of transfixing.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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