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There are 12 eight-letter words containing A, O, P, S and X

APOMIXESapomixes n. Plural of apomixis.
APOMIXIS n. (Greek) nonsexual reproduction, from an apomict or unfertilized ovum.
APOMIXISapomixis n. (Botany) Plant reproduction without fertilization.
apomixis n. (Botany) Plant reproduction without fertilization, meiosis, or the production of gametes.
apomixis n. (Zoology) Animal reproduction in which the egg cell does not undergo meiosis or fertilization.
AXOPLASMaxoplasm n. The cytoplasm of an axon.
AXOPLASM n. the cytoplasm of an axon, a nerve fibre.
EXOCARPSexocarps n. Plural of exocarp.
EXOCARP n. the outer portion of a fruit, as the flesh of a peach or the rind of an orange.
EXOPLASMexoplasm n. Alternative form of ectoplasm.
EXOPLASM n. the outer transparent layer of protoplasm in a developing ovum, also ECTOPLASM.
EXPOSALSexposals n. Plural of exposal.
EXPOSAL n. exposure.
HEXAPODShexapods n. Plural of hexapod.
HEXAPOD n. an animal with six feet, an insect.
HYPOXIAShypoxias n. Plural of hypoxia.
HYPOXIA n. a deficiency of oxygen in the body tissues, also HYPOXAEMIA, HYPOXEMIA.
PAROXYSMparoxysm n. A random or sudden outburst (of activity).
paroxysm n. An explosive event during a volcanic eruption.
paroxysm n. A sudden recurrence of a disease, such as a seizure or a coughing fit.
POLEAXESpoleaxes n. Plural of poleax.
pole-axes n. Plural of pole-axe.
POLEAX v. to strike with an axlike weapon, also POLEAXE.
POLLAXESpollaxes n. Plural of pollax.
pollaxes n. Plural of pollaxe.
POLLAXE v. to strike with a pollaxe.
SMALLPOXsmallpox n. (Pathology) An acute, highly infectious often fatal disease caused by Variola virus of the family Poxviridae…
small-pox n. Obsolete spelling of smallpox.
small␣pox n. Obsolete spelling of smallpox.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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