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There are 17 eight-letter words containing A, E, M, T and X

EXAMETREexametre n. 1018 metres.
EXAMETRE n. ten to the power of eighteen metres.
EXANTHEMexanthem n. A widespread rash usually occurring in children.
EXANTHEM n. a skin eruption, esp. accompanied by fever, also EXANTHEMA.
EXHUMATEexhumate v. (Obsolete) To exhume; to disinter.
EXHUMATE v. to dig out from the earth, also EXHUME.
EXTREMALextremal adj. (Mathematics) Relating to extrema (maximal or minimal).
extremal n. (Mathematics) Any solution to a variety of equations in the calculus of variations.
EXTREMAL n. a clause which limits recursion.
MALAXATEmalaxate v. To soften, especially by kneading with the hands.
MALAXATE v. to soften by kneading, also MALAX.
MANTEAUXmanteaux n. Plural of manteau.
MANTEAU n. (French) a woman's loose gown, also MANTO, MANTUA, MANTY.
MARTEXTSmartexts n. Plural of martext.
MARTEXT n. an ignorant preacher.
MASTIXESMASTIX n. (French) a pale yellow gum resin from certain Mediterranean trees, used for varnish, also MASTIC, MASTICH, MASTICHE.
MATRIXESmatrixes n. Plural of matrix.
MATRIX n. (Latin) the womb; that in which anything is embedded, also MATRICE.
MAXIMITEMAXIMITE n. a powerful explosive.
MEATAXESmeataxes n. Plural of meataxe.
meat␣axes n. Plural of meat axe.
MEATAXE n. a meat cleaver.
MIXTAPESmixtapes n. Plural of mixtape.
mix␣tapes n. Plural of mix tape.
MIXTAPE n. a compilation of songs from various sources.
TOXAEMIAtoxaemia n. Alternative spelling of toxemia, organic blood poisoning.
toxæmia n. Obsolete form of toxemia.
TOXAEMIA n. the condition of having toxins in the blood, also TOXEMIA.
TOXAEMICtoxaemic adj. Alternative spelling of toxemic.
toxæmic adj. Obsolete form of toxemic.
TOXAEMIC adj. relating to toxaemia, blood poisoning due to toxins in blood, also TOXEMIC.
TOXEMIAStoxemias n. Plural of toxemia.
TOXEMIA n. blood poisoning due to toxins in blood, also TOXAEMIA.
TRUMEAUXtrumeaux n. Plural of trumeau.
TRUMEAU n. (French) a column supporting part of a doorway.
XEROMATAXEROMA n. (Greek) a dry lustreless condition of the conjunctiva, also XEROPHTHALMIA.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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