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There are 8 eight-letter words containing A, 2C, F and I

CALCIFICcalcific adj. Of or pertaining to calcification.
calcific adj. Of or pertaining to the formation of eggshells in birds and reptiles.
CALCIFIC adj. containing salts of calcium.
CALFLICKcalflick n. Synonym of cowlick (“unruly lock of hair”).
CALFLICK n. a cowlick (a lock of unruly hair).
EFFICACYefficacy n. Ability to produce a desired effect under ideal testing conditions.
efficacy n. Degree of ability to produce a desired effect; effectiveness.
EFFICACY n. effectiveness.
FACTICESfactices n. Plural of factice.
FACTICE n. vulcanized oil, used as substitute for rubber, also FACTIS.
FARCICALfarcical adj. Resembling a farce; ludicrous; absurd.
farcical adj. (Veterinary medicine, obsolete, rare) Pertaining to farcy.
FARCICAL adj. absurd.
FASCICLEfascicle n. A bundle or cluster.
fascicle n. (Anatomy) A bundle of skeletal muscle fibers surrounded by connective tissue.
fascicle n. (Botany) A cluster of flowers or leaves, such as the bundles of the thin leaves (or needles) of pines.
FOCACCIAfocaccia n. (Uncountable) A flatbread similar in style, composition, and texture to modern pizza doughs and topped…
focaccia n. (Countable) A sandwich made with this type of bread.
FOCACCIA n. (Italian) a flat Italian bread.
LACTIFIClactific adj. Producing or yielding milk.
LACTIFIC adj. producing milk.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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