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There are 2 six-letter words containing 2A, N, O and P

ANOPIAanopia n. (Medicine) State or condition of sightlessness, often due to medical reasons.
ANOPIA n. a visual defect, an upward squint, also ANOOPSIA, ANOPSIA.
APNOEAapnoea n. (British spelling) Alternative form of apnea.
apnœa n. Obsolete spelling of apnea.
APNOEA n. a temporary cessation of breathing, also APNEA.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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