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There are 6 six-letter words containing 2A, C, L and T

ACETALacetal n. (Organic chemistry) Any diether of a geminal diol, R2C(OR’)2 (where R’ is not H).
ACETAL n. an odoriferous liquid formed by reaction of acetaldehyde and ethyl alcohol.
ACTUALactual adj. (Chiefly theology) relating to a person’s acts or deeds; active, practical.
actual adj. Existing in reality, not just potentially; really acted or acting; occurring in fact.
actual adj. (Now rare) in action at the time being; now existing; current.
CALTHAcaltha n. (Botany) A plant of the genus Caltha; a marsh marigold.
Caltha prop.n. A taxonomic genus within the family Ranunculaceae – flowering plants resembling marigolds (genera Calendula…
CALTHA n. (Latin) a genus of plants including the marsh marigold.
CANTALcantal n. Alternative letter-case form of Cantal.
Cantal n. A type of cheese originally made in the south of France.
Cantal prop.n. One of the départements in Auvergne-Rhône-Alpes, France (INSEE code 15).
CATALOcatalo n. (Dated) Alternative form of cattelo.
CATALO n. a cross between a buffalo and a domestic cow, also CATTALO.
LACTAMlactam n. (Organic chemistry) Any of a class of cyclic amides that are the nitrogen analogs of lactones, formed…
LACTAM n. one of a series of anhydrides of an amido type, analogous to the lactones.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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