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There are 17 fifteen-letter words containing 2A, D, E and X

DECARBOXYLATINGdecarboxylating v. Present participle of decarboxylate.
DECARBOXYLATE v. to remove carbon dioxide from its substrate.
DECARBOXYLATIONdecarboxylation n. (Organic chemistry) The removal of one or more carboxyl groups from a molecule.
DECARBOXYLATION n. the removal or elimination of carboxyl from a molecule.
DESEXUALISATIONdesexualisation n. Alternative spelling of desexualization.
DESEXUALISATION n. the act of desexualising, also DESEXUALIZATION.
DESEXUALIZATIONdesexualization n. The act or process of desexualizing.
DESEXUALIZATION n. the act of desexualizing, also DESEXUALISATION.
DEXAMPHETAMINESDEXAMPHETAMINE n. the dextrorotatory isomer of amphetamine, used as a stimulant.
EXAGGERATEDNESSexaggeratedness n. The quality of being exaggerated.
EXAGGERATEDNESS n. the state of being exaggerated.
EXPANDABILITIESexpandabilities n. Plural of expandability.
EXPANDABILITY n. the state of being expandable.
EXTRAJUDICIALLYextrajudicially adv. Outside of the legal system.
EXTRAJUDICIAL adv. not forming a valid part of regular legal proceedings.
EXTRAORDINARIESextraordinaries n. Plural of extraordinary.
extra-ordinaries n. Plural of extra-ordinary.
EXTRAORDINARY n. something out of the ordinary.
EXTRAORDINARILYextraordinarily adv. In an extraordinary manner.
EXTRAORDINARY adv. going beyond what is usual, regular, or customary.
HEXOSAMINIDASEShexosaminidases n. Plural of hexosaminidase.
HEXOSAMINIDASE n. either of two hydrolytic enzymes that catalyze the splitting off of a hexose from a ganglioside and are deficient in some metabolic diseases.
HYDROXYAPATITEShydroxyapatites n. Plural of hydroxyapatite.
HYDROXYAPATITE n. a complex phosphate of calcium that occurs as a mineral and is the chief structural element of vertebrate bone.
HYDROXYLAPATITEhydroxylapatite n. Alternative spelling of hydroxyapatite.
HYDROXYLAPATITE n. a mineral of the apatite group that is rare in the ground but is the principal inorganic constituent of tooth enamel and bone.
OVEREXAGGERATEDoverexaggerated v. Simple past tense and past participle of overexaggerate.
OVEREXAGGERATE v. to exaggerate excessively.
PARADOXICALNESSparadoxicalness n. The state or quality of being paradoxical.
PARADOXICAL n. of the nature of a paradox, also PARADOXAL.
UNEXTRAORDINARYunextraordinary adj. Not extraordinary; mundane, ordinary.
UNEXTRAORDINARY adj. not extraordinary.
XERORADIOGRAPHYxeroradiography n. A method of X-ray photography which uses an electrically charged metal plate instead of film.
XERORADIOGRAPHY n. radiography used esp. in mammographic screening for breast cancer that produces an image using X-rays in a manner similar to the way an image is produced by light in xerography.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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