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There are 11 twelve-letter words containing 2A, E, M and Q

DESQUAMATINGdesquamating v. Present participle of desquamate.
DESQUAMATE v. to scale or flake off.
DESQUAMATIONdesquamation n. (Medicine) The shedding of the outer layers of the skin.
DESQUAMATION n. having one's skin fall off due to its being waterlogged.
DESQUAMATIVEdesquamative adj. Of, relating to, or attended with, desquamation.
DESQUAMATIVE adj. serving to desquamate.
DESQUAMATORYdesquamatory adj. (Surgery) Relating to the removal of the laminae of exfoliated bones.
DESQUAMATORY n. an obsolete surgical instrument once used for the desquamation of bones.
MACABERESQUEmacaberesque adj. Macabre.
macaberesque n. The danse macabre, or some similar performance or imagery.
MACABERESQUE adj. somewhat macaber.
MARQUESSATESmarquessates n. Plural of marquessate.
MARQUESSATE n. the rank of marquess.
MASQUERADERSmasqueraders n. Plural of masquerader.
MASQUERADER n. one who masquerades.
MASQUERADINGmasquerading v. Present participle of masquerade.
masquerading n. The act of one who masquerades.
MASQUERADE v. to disguise oneself.
METASEQUOIASmetasequoias n. Plural of metasequoia.
METASEQUOIA n. a tree, the dawn redwood.
METHAQUALONEmethaqualone n. (Pharmacology) A sedative drug that has effects similar to barbiturates. Also used recreationally.
METHAQUALONE n. a type of sedative, aka quaalude.
QUARRYMASTERquarrymaster n. The person in charge of a quarry.
QUARRYMASTER n. one in charge of a quarry.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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