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There are 19 twelve-letter words containing 2A, 2C and F

CALEFACIENTScalefacients n. Plural of calefacient.
CALEFACIENT n. a substance (e.g. mustard) that produces a sensation of warmth when applied to a part of the body.
CALEFACTIONScalefactions n. Plural of calefaction.
CALEFACTION n. the act of heating.
CHARACTERFULcharacterful adj. Full of character.
CHARACTERFUL adj. full of character.
COSURFACTANTcosurfactant n. A surfactant acting in tandem with another surfactant to enhance its properties.
COSURFACTANT n. something that works in combination with a surfactant.
CRANIOFACIALcraniofacial adj. (Medicine) Pertaining to the cranium and face, as with craniofacial surgery.
CRANIOFACIAL adj. of, relating to, or involving both the cranium and the face.
FACTUALISTICfactualistic adj. Of or relating to factualism.
FACTUALISTIC adj. factual.
FARCICALNESSfarcicalness n. The property of being farcical.
FARCICALNESS n. the state of being farcical.
FASCICULARLYfascicularly adv. Having, or in terms of, fascicles.
FASCICULAR adv. in bundles, also FASCICULATE, FASCICULATED.
FASCICULATEDfasciculated adj. Grouped in a fascicle; fascicled.
FASCICULATED adj. in bundles, also FASCICULAR, FASCICULATE.
PACIFICATINGpacificating v. Present participle of pacificate.
pacificating adj. (Archaic) Which makes peace; which pacificates.
PACIFICATE v. to give peace to.
PACIFICATIONpacification n. The process of pacifying.
PACIFICATION n. the act of pacifying.
PACIFICATORSpacificators n. Plural of pacificator.
PACIFICATOR n. a peacemaker.
PACIFICATORYpacificatory adj. Promoting peace; conciliatory.
PACIFICATORY adj. tending to make peace.
SACCHARIFIEDsaccharified v. Simple past tense and past participle of saccharify.
saccharified adj. Converted into simple sugars.
SACCHARIFY v. to convert into, or to impregnate with, sugar.
SACCHARIFIESsaccharifies v. Third-person singular simple present indicative form of saccharify.
SACCHARIFY v. to convert into, or to impregnate with, sugar.
SAFECRACKERSsafecrackers n. Plural of safecracker.
safe-crackers n. Plural of safe-cracker.
SAFECRACKER n. one that breaks open safes to steal.
SAFECRACKINGsafecracking n. The act of defeating the security mechanisms of a safe or vault to gain access to its contents.
SAFECRACKING n. the act of breaking open a safe.
SCARIFICATORscarificator n. (Surgery, archaic) An instrument, principally used in cupping, containing several lancets that are moved…
SCARIFICATOR n. a surgical instrument for scarifying, also SCARIFIER.
TRANSPACIFICtranspacific adj. (Geography) On, from the other side of, spanning or crossing the Pacific Ocean.
trans-Pacific adj. Alternative form of transpacific.
TRANSPACIFIC adj. crossing or extending across the Pacific Ocean.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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