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There are 20 fifteen-letter words containing A, 2F and R

AFFORDABILITIESaffordabilities n. Plural of affordability.
AFFORDABILITY n. the quality of being affordable.
AFFRANCHISEMENTaffranchisement n. The act of freeing; enfranchisement.
AFFRANCHISEMENT n. the act of affranchising.
DEDIFFERENTIATEdedifferentiate v. To lose or reverse differentiation.
DEDIFFERENTIATE v. to effect dedifferentiation, a change by which specialized tissue with several cell types reverts to a generalized and simpler form.
DEXFENFLURAMINEdexfenfluramine n. A serotonergic anorectic drug used for weight loss in the 1990s, later withdrawn because of cardiovascular…
DIFFERENTIATINGdifferentiating v. Present participle of differentiate.
DIFFERENTIATE v. to obtain the mathematical derivative of.
DIFFERENTIATIONdifferentiation n. The act or process of differentiating (generally, without a specialized sense).
differentiation n. (Biology) The process by which the components of multicellular life (Cells, organs, etc.) are produced…
differentiation n. (Biology, evolution) The evolutionary process by which one taxonomic group (Species, genus, variety…
DIFFERENTIATORSdifferentiators n. Plural of differentiator.
DIFFERENTIATOR n. someone who or that which differentiates.
DIFFRACTIVENESSDIFFRACTIVE n. causing diffraction.
DIFFRACTOMETERSdiffractometers n. Plural of diffractometer.
DIFFRACTOMETER n. an instrument for determining structure of crystal through light diffraction.
DIFFRACTOMETRICdiffractometric adj. Relating to diffractometry; measured using a diffractometer.
DIFFRACTOMETRIC adj. relating to measurement by diffractometer, an instrument for determining structure of crystal through light diffraction.
DIFFRANGIBILITYdiffrangibility n. Ability to be diffracted.
DIFFRANGIBILITY n. the state of being diffrangible, capable of being diffracted or separated.
DISAFFIRMATIONSdisaffirmations n. Plural of disaffirmation.
DISAFFIRMATION n. the act of disaffirming.
DISAFFORESTMENTdisafforestment n. Disafforestation.
DISAFFORESTMENT n. the act of disafforesting.
FORISFAMILIATEDforisfamiliated v. Simple past tense and past participle of forisfamiliate.
FORISFAMILIATE v. (Scots) to emancipate from parental authority.
FORISFAMILIATESforisfamiliates v. Third-person singular simple present indicative form of forisfamiliate.
FORISFAMILIATE v. (Scots) to emancipate from parental authority.
FRENCHIFICATIONFrenchification n. The act or process of making French or more French-like, especially in informal contexts.
Frenchification n. (Slang) Something that has undergone frenchification, something that has frenchified and made more French-like.
Frenchification n. Synonym of Gallicization, translation into French or a French translation.
FRUCTIFICATIONSfructifications n. Plural of fructification.
FRUCTIFICATION n. the reproductive organs or fruit of a plant.
FURFURALDEHYDESFURFURALDEHYDE n. a liquid obtained by heating bran with dilute sulphuric acid, also FURAL, FURFURAL, FURFUROL, FURFUROLE, FUROL, FUROLE.
REAFFORESTATIONreafforestation n. Reforestation.
REAFFORESTATION n. the act of reafforesting.
REFORTIFICATIONrefortification n. A second or subsequent fortification.
REFORTIFICATION n. the act of refortifying.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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