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There are 2 six-letter words beginning with CANCE

CANCELcancel v. (Transitive) To cross out something with lines etc.
cancel v. (Transitive) To invalidate or annul something.
cancel v. (Transitive) To mark something (such as a used postage stamp) so that it can’t be reused.
CANCERcancer n. (Medicine, oncology, pathology) A disease in which the cells of a tissue undergo uncontrolled (and often…
cancer n. (Figuratively) Something damaging that spreads throughout something else.
cancer adj. (Slang) Extremely unpleasant and annoying.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org.

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