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There are 16 ten-letter words containing P, 2S, T and 2U

OUTPURSUESOUTPURSUE v. to pursue further than.
POSTHUMOUSposthumous adj. After the death of someone.
posthumous adj. Taking place after one’s own death.
posthumous adj. In reference to a work, published after the author’s death.
POUTASSOUSPOUTASSOU n. a gadoid fish, aka blue whiting.
PRURITUSESprurituses n. Plural of pruritus.
PRURITUS n. (Latin) intense itching.
PUSTULANTSpustulants n. Plural of pustulant.
PUSTULANT n. an agent that causes pustules.
PUSTULATESpustulates v. Third-person singular simple present indicative form of pustulate.
PUSTULATE v. to form into pustules, or blisters.
SCULPTURESsculptures n. Plural of sculpture.
sculptures v. Third-person singular simple present indicative form of sculpture.
SCULPTURE v. to carve in stone.
SEPULTURESsepultures n. Plural of sepulture.
SEPULTURE v. to bury, inter.
SPIRITUOUSspirituous adj. Of, pertaining to, containing, or made using alcohol.
spirituous adj. (Of an alcoholic drink) Distilled.
SPIRITUOUS adj. alcoholic.
STROPHULUSstrophulus n. (Medicine) An eruption of red pimples upon the face, neck, and arms, in early infancy; tooth rash; red-gum.
STROPHULUS n. a skin inflammation found primarily on small children.
STUPENDOUSstupendous adj. Astonishingly great or large; huge; enormous.
stupendous adj. Of stunning excellence or degree; marvelous.
STUPENDOUS adj. causing astonishment or wonder, also STUPENDIOUS.
SULPHURETSsulphurets n. Plural of sulphuret.
SULPHURET v. to treat with sulfur, also SULFURET.
SUPERSCOUTsuperscout n. (Informal) An exceptionally talented or successful scout (one who seeks out potential talent for a sports team).
SUPERSCOUT n. a superlative scout.
SUPERSTUDSsuperstuds n. Plural of superstud.
SUPERSTUD n. an exceptionally virile male.
SUPPURATESsuppurates v. Third-person singular simple present indicative form of suppurate.
SUPPURATE v. to discharge pus.
SUSPECTFULsuspectful adj. (Now rare) Mistrustful, suspicious.
SUSPECTFUL adj. apt to suspect or mistrust.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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