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There are 17 words containing 3I, 2P, S and U

APPROPINQUITIESAPPROPINQUITY n. nearness.
DISPAUPERISINGdispauperising v. Present participle of dispauperise.
DISPAUPERISE v. to free from pauperdom, also DISPAUPERIZE.
DISPAUPERIZINGdispauperizing v. Present participle of dispauperize.
DISPAUPERIZE v. to free from pauperdom, also DISPAUPERISE.
EUPEPTICITIESEUPEPTICITY n. the state of being eupeptic.
HYPOPITUITARISMhypopituitarism n. (Medicine) A decrease in secretion of one or more of the eight hormones normally produced by the pituitary gland.
HYPOPITUITARISM n. deficient production of growth hormones by the pituitary gland.
INOPPORTUNITIESINOPPORTUNITY n. the state of being inopportune.
PERSPICUITIESperspicuities n. Plural of perspicuity.
PERSPICUITY n. the state of being perspicuous, clear, easily understood.
PROPINQUITIESpropinquities n. Plural of propinquity.
PROPINQUITY n. nearness in space, time or relationship.
PROPITIATIOUSPROPITIATIOUS adj. serving to propitiate, also PROPITIATIVE, PROPITIATORY.
PUPILABILITIESPUPILABILITY n. an intentionally unintelligible word in Sterne's Tristram Shandy.
PUPILARITIESPUPILARITY n. the state of being a pupil or legal ward, also PUPILLARITY.
PUPILLARITIESpupillarities n. Plural of pupillarity.
PUPILLARITY n. the state of being a pupil or legal ward, also PUPILARITY.
SUPERIMPOSITIONsuperimposition n. The process, or the result of superimposing.
superimposition n. The placing of one image on top of another, especially placing a photograph over some other graphic.
superimposition n. (Philosophy) The building of ontological categories of a higher level on top of categories of a lower level.
SUPPOSITITIOUSsupposititious adj. (Obsolete) Spurious; substituted for the genuine, counterfeit; fake.
supposititious adj. (Obsolete) Imaginary; fictitious, pretended to exist.
supposititious adj. Supposed or hypothetical.
SUPPRESSIBILITYsuppressibility n. Quality of being suppressible.
SUPPRESSIBILITY n. the state of being suppressible.
UNDISAPPOINTINGundisappointing adj. Not disappointing.
UNDISAPPOINTING adj. not disappointing.
YUPPIFICATIONSYUPPIFICATION n. the process of conversion into a yuppy.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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