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There are 17 twelve-letter words containing 2E, 2I, 2M and N

DEMIMONDAINEdemimondaine n. A sexually promiscuous woman (of the demimonde).
demi-mondaine n. Alternative form of demimondaine.
DEMIMONDAINE n. (French) a demirep, a woman of doubtful reputation.
DETERMINISMSdeterminisms n. Plural of determinism.
DETERMINISM n. the doctrine that all things, including the will, are determined by causes.
DISMEMBERINGdismembering v. Present participle of dismember.
dismembering n. The act or process whereby something is dismembered.
DISMEMBER v. to cut or tear a body limb from limb.
ECOFEMINISMSecofeminisms n. Plural of ecofeminism.
ECOFEMINISM n. a movement or theory that applies feminist principles and ideas to ecological issues.
ECUMENICISMSecumenicisms n. Plural of ecumenicism.
ECUMENICISM n. the doctrines and practice of the Christian ecumenical movement, also ECUMENICALISM.
IMMINENTNESSimminentness n. The quality of being imminent.
IMMINENTNESS n. the state of being imminent.
IMPEDIMENTALimpedimental adj. Of the nature of an impediment; hindering or obstructing.
IMPEDIMENTAL adj. causing hindrance; impeding.
IMPERILMENTSimperilments n. Plural of imperilment.
IMPERILMENT n. the act of imperilling.
IMPINGEMENTSimpingements n. Plural of impingement.
IMPINGEMENT n. the act of impinging.
IMPLEMENTINGimplementing v. Present participle of implement.
IMPLEMENT v. to put into practice.
INTERMEDIUMSintermediums n. Plural of intermedium.
INTERMEDIUM n. a small bone in the wrist and ankle.
MISBESEEMINGmisbeseeming v. Present participle of misbeseem.
MISBESEEM v. (archaic) to be unsuited to.
MISDEMEANINGmisdemeaning v. Present participle of misdemean.
MISDEMEAN v. to behave ill, with a reflexive pronoun; as, to misdemean one's self.
MISESTEEMINGmisesteeming v. Present participle of misesteem.
MISESTEEM v. to lack esteem for; to disrespect.
MISTEMPERINGmistempering v. Present participle of mistemper.
MISTEMPER v. (obsolete) to temper ill; to disorder.
REIMMERSIONSreimmersions n. Plural of reimmersion.
SIMPLEMINDEDsimpleminded adj. Stupid.
simpleminded adj. Unsophisticated; lacking subtlety.
simple-minded adj. Lacking subtlety or sophistication.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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