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There are 2 twelve-letter words containing B, C, 2E, I, O and X

EXACERBATIONexacerbation n. An increase in the severity of something (such as a disease).
EXACERBATION n. the act of exarcebating.
EXORBITANCESexorbitances n. Plural of exorbitance.
EXORBITANCE n. an exorbitant action or procedure, also EXORBITANCY.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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