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There are 3 twelve-letter words containing A, C, P, R and 3U

ACUPUNCTURALacupunctural adj. Relating to acupuncture.
ACUPUNCTURAL adj. relating to acupuncture.
ACUPUNCTURESacupunctures n. Plural of acupuncture.
acupunctures v. Third-person singular simple present indicative form of acupuncture.
ACUPUNCTURE n. the complementary therapy of puncturing the skin with needles at specified points in order to cure illness.
SUPERNACULUMsupernaculum adv. (Obsolete) According to the rules of an old drinking game in which the drinker upturned the empty cup…
supernaculum adv. To the last drop, to the bottom.
supernaculum n. (Obsolete) Excellent wine that one would wish to drink to the last drop.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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